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Article

Loss of the Y chromosome is a frequent chromosomal imbalance in pancreatic cancer and allows differentiation to chronic pancreatitis

1 Feb 2001

Abstract excerpt

In a study for the identification of genomic alterations in pancreatic cancer, representational difference analysis was used and led to the isolation of 2 distinct fragments, deleted on the Y chromosome in the xenografted tumor DNA of a male patient with an adenocarcinoma of the pancreas. Loss of Y chromosomal material was further studied in 11 pancreatic cancer cell lines of male origin, using PCR amplification...

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Share to Cancer Genomics and Diagnostics
Share to Genomic variations and chromosomal abnormalities
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Identifiers

PMID: 11169957
DOI: 10.1002/1097-0215(200002)9999:9999<::aid-ijc1014>3.0.co;2-u

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

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