Article
Epstein-Barr virus types 1 and 2 have nearly identical LMP-1 transforming genes.
The Journal of general virology - 1 Oct 1994
Sample J, Kieff E F, Kieff E D
Abstract excerpt
Although variation in the gene encoding the Epstein-Barr virus (EBV) nuclear protein 2 accounts for much of the difference in the transforming activities of the two EBV strain types, divergence in the principal lymphocyte growth-altering gene, LMP-1, has not been previously evaluated. We have now determined the nucleotide sequence of the LMP-1 gene of a type 2 isolate of EBV, AG876. Surprisingly, the AG876 LMP-1...
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