Article
Retrieval of HDEL proteins is required for growth of yeast cells.
The Journal of cell biology - 1 Oct 1994
Townsley F M, Frigerio G, Pelham H R
Abstract excerpt
The ERD2 gene of Saccharomyces cerevisiae encodes the receptor which retrieves HDEL-containing containing ER proteins from the Golgi apparatus. Viable erd2 mutants have been isolated that show no obvious HDEL-dependent retention of the luminal ER protein BiP, suggesting that retrieval of HDEL pro...
Topics
- Amino Acid Sequence
- Fungal Proteins
- Genes, Fungal
- Golgi Apparatus
- HSP70 Heat-Shock Proteins
- Heat-Shock Proteins
- Membrane Proteins
- Models, Biological
- Molecular Sequence Data
- Mutation
- Oligopeptides
- Protein Sorting Signals
- Receptors, Peptide
- Recombinant Fusion Proteins
- Saccharomyces cerevisiae
- Saccharomyces cerevisiae Proteins