Article
Features of vacuolar H(+)-ATPase revealed by yeast suppressor mutants.
The Journal of biological chemistry - 21 Oct 1994
Supek F, Supekova L, Nelson N
Abstract excerpt
The yeast Saccharomyces cerevisiae serves as an excellent model for the study of the structure and function of proteins. Numerous amino acid substitutions in the proteolipid subunit of yeast vacuolar H(+)-ATPase have been reported. Suppressed variants for several of the inactive mutants were sele...
Topics
- Amino Acid Sequence
- Molecular Sequence Data
- Mutation
- Phenotype
- Protein Structure, Secondary
- Proteolipids
- Proton-Translocating ATPases
- Saccharomyces cerevisiae
- Structure-Activity Relationship
- Vacuoles