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Article

Additive effect of tolC and rfa mutations on the hydrophobic barrier of the outer membrane of Escherichia coli K-12.

Journal of bacteriology - 1 Oct 1994

Fralick J A, Burns-Keliher L L

Abstract excerpt

Studies using tolC mutant derivatives of deep rough (rfa) mutants indicate that tolC and rfa mutations have an additive effect with respect to their sensitivity to hydrophobic agents, suggesting that they are not acting through a mutual mechanism to alter the permeability of the outer membrane.

Topics

Bacterial Outer Membrane Proteins
Biological Transport
Carbohydrate Sequence
Cell Division
Cell Membrane
Deoxycholic Acid
Escherichia coli
Escherichia coli Proteins
Kanamycin
Lipopolysaccharides
Membrane Transport Proteins

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Mutation

Novobiocin

Sodium Dodecyl Sulfate

Source

Open in PubMed Open full text

Identifiers

PMID: 7929014
DOI: 10.1128/jb.176.20.6404-6406.1994
PMCID: PMC196984

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7929014-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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Additive effect of tolC and rfa mutations on the hydrophobic barrier of the outer membrane of Escherichia coli K-12.PMID 7929014Read ↗

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