Article
Capillary zone electrophoresis of polymerase chain reaction-amplified DNA fragments in polymer networks: the case of GATT microsatellites in cystic fibrosis.
Electrophoresis - 1 May 1994
Gelfi C, Orsi A, Righetti P G, Brancolini V, Cremonesi L, Ferrari M
Abstract excerpt
In cystic fibrosis (CF), the most common mutation, delta F508 (a three-base-pair deletion) accounts for ca. 70% of mutations in the worldwide population. The majority of other mutations (more than 350 reported so far to the Genetic Analysis Consortium) have been detected in single cases, thus ren...
Topics
- Alleles
- Base Sequence
- Cystic Fibrosis
- DNA, Satellite
- Electrophoresis, Polyacrylamide Gel
- Molecular Sequence Data
- Mutation
- Oligonucleotides
- Polymerase Chain Reaction
- Polymorphism, Genetic
- Repetitive Sequences, Nucleic Acid