The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis.

doi:10.1016/0092-8674(94)90397-2

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Article

The Drosophila easily shocked gene: a mutation in a phospholipid synthetic pathway causes seizure, neuronal failure, and paralysis.

Cell - 7 Oct 1994

Pavlidis P, Ramaswami M, Tanouye M A

Abstract excerpt

We have characterized easily shocked (eas), a Drosophila "band-sensitive" paralytic mutant. Electrophysiological recordings from flight muscles in the giant fiber pathway of adult eas flies reveal that induction of paralysis with electrical stimulation results in a brief seizure, followed by a failure of the muscles to respond to giant fiber stimulation. Molecular cloning, germline transformation, and biochemical...

Topics

Amino Acid Sequence
Animals
Base Sequence
Chromosome Mapping
Cloning, Molecular
DNA, Complementary
Drosophila melanogaster
Electric Stimulation
Female
Genes, Insect
Genes, Lethal

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Male

Molecular Sequence Data

Mutation

Paralysis

Phenotype

Phospholipids

Phosphotransferases (Alcohol Group Acceptor)

Source

Open in PubMed

Identifiers

PMID: 7923374
DOI: 10.1016/0092-8674(94)90397-2

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7923374-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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