Article
Separation of lectin-binding cells using polystyrene culture devices with covalently immobilized soybean agglutinin.
Journal of hematotherapy - 1 Jan 1994
Schain L R, Okrongly D, Okarma T B, Lebkowski J S
Abstract excerpt
The plant lectin, soybean agglutinin (SBA), has been widely used to separate heterogeneous populations of cells. In the field of bone marrow transplantation, SBA has been used for partial depletion of T cells from bone marrow allografts to reduce graft-vs.-host disease. SBA's high affinity for many different tumor cells has also indicated its use as a tumor purging agent for autologous bone marrow transplants. We...
Topics
- Antigens, CD
- Bone Marrow
- Bone Marrow Cells
- Cell Separation
- Cell Size
- Cells, Cultured
- Hematopoiesis
- Humans
- Lectins
- Phenotype
- Plant Lectins
- Polystyrenes