Fractionation of mouse bone marrow by adherence separates primitive hematopoietic stem cells from in vitro colony-forming cells and spleen colony-forming cells.

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Article

Fractionation of mouse bone marrow by adherence separates primitive hematopoietic stem cells from in vitro colony-forming cells and spleen colony-forming cells.

Blood - 15 Nov 1991

Kiefer F, Wagner E F, Keller G

Abstract excerpt

Fractionation of mouse bone marrow by adherence to tissue culture plastic was used to characterize the adhesive properties of hematopoietic stem (HS) cells capable of long-term reconstitution. The adherent fraction that represents approximately 13% of the total marrow population was virtually devoid of in vitro colony-forming cells and spleen colony-forming cells but did contain approximately 30% of the total HS...

Topics

Alleles
Animals
Bone Marrow
Bone Marrow Cells
Bone Marrow Transplantation
Cell Adhesion
Cell Separation
Cells, Cultured
Genotype
Glucose-6-Phosphate Isomerase
Hematopoietic Stem Cells

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Isoenzymes

Kinetics

Mice

Mice, Inbred C57BL

Spleen

Stem Cells

Source

Open in PubMed

Identifiers

PMID: 1824253

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-1824253-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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