Simultaneous genotypic and immunophenotypic analysis of interphase cells for the detection of contaminating maternal cells in cord blood and their respective CFU-GM and BFU-E.

doi:10.1089/scd.1.1993.2.235

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Article

Simultaneous genotypic and immunophenotypic analysis of interphase cells for the detection of contaminating maternal cells in cord blood and their respective CFU-GM and BFU-E.

Journal of hematotherapy - 1 Jan 1993

Kögler G, Göbel U, Somville T, Enczmann J, Arkesteijn G, Wernet P

Abstract excerpt

Contamination of cord blood (CB) specimens by maternal blood provides a source of cells that may be capable of graft-versus-host reactivity. To confirm the genetic purity of collected CB samples (six samples, volume 110 +/- 21 ml, total nucleated cells 1.22 +/- 0.36 x 10(9)) the HLA-DR beta exon...

Topics

Adult
Colony-Forming Units Assay
Erythroid Precursor Cells
Female
Fetal Blood
Genotype
Graft vs Host Reaction
HLA-DR Antigens
Hematopoietic Stem Cells
Humans
Immunophenotyping
In Situ Hybridization, Fluorescence
Infant, Newborn
Interphase
Male
Maternal-Fetal Exchange
Microscopy, Confocal
Pregnancy

Source

Open in PubMed

Identifiers

PMID: 7921983
DOI: 10.1089/scd.1.1993.2.235

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7921983-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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