Article
Human dermatophyte-responsive T-cell lines recognize cross-reactive antigens associated with mannose-rich glycoproteins.
Experimental dermatology - 1 Apr 1994
MacCarthy K G, Blake J S, Johnson K L, Dahl M V, Kalish R S
Abstract excerpt
Resistance to dermatophyte infections has been shown to be mediated in part by T lymphocytes. The dermatophyte antigens recognized by human T lymphocytes and their degree of cross-reactivity were analyzed. Dermatophyte-responsive T-cell lines were generated by in vitro sensitization to crude fungal extracts obtained from Trichophyton rubrum, Trichophyton tonsurans, Microsporum canis and Epidermophyton floccosum....
Topics
- Adult
- Antigens, Fungal
- Arthrodermataceae
- Cell Division
- Cell Line
- Cross Reactions
- Epidermophyton
- Glycoproteins
- Humans
- Male
- Mannans
- Mannose
