Low normal alpha-1-antitrypsin serum concentrations and MZ-phenotype are associated with byssinosis and familial allergy in cotton mill workers.

doi:10.1097/00008571-199406000-00004

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Article

Low normal alpha-1-antitrypsin serum concentrations and MZ-phenotype are associated with byssinosis and familial allergy in cotton mill workers.

Pharmacogenetics - 1 Jun 1994

Sigsgaard T, Brandslund I, Rasmussen J B, Lund E D, Varming H

Abstract excerpt

Recent studies have shown a close association between byssinosis and airborne endotoxin concentrations. Endotoxin might induce byssinosis through the release of biochemical mediators as the broncheoalveolar surface. Alpha-1-antitrypsin (alpha-1-A) which neutralizes enzymes released by granulocyte...

Topics

Adult
Air Pollutants, Occupational
Byssinosis
Endotoxins
Female
Gossypium
Humans
Hypersensitivity
Male
Middle Aged
Occupational Diseases
Phenotype
alpha 1-Antitrypsin

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