Article
Induction of heat shock proteins by abnormal proteins results from stabilization and not increased synthesis of sigma 32 in Escherichia coli.
Journal of bacteriology - 1 Sept 1994
Kanemori M, Mori H, Yura T
Abstract excerpt
Accumulation of abnormal proteins in cells of bacteria or eukaryotes can induce synthesis of a set of heat shock proteins. We examined such induction following addition of azetidine (a proline analog) or synthesis of a heterologous protein (human prourokinase) in Escherichia coli. Synthesis of heat shock proteins under these conditions increased almost immediately and continued with increasing rates until it...
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