Article
Molecular biology of breast cancer.
Annals of oncology : official journal of the European Society for Medical Oncology - 1 Jan 1994
Lemoine N R
Abstract excerpt
BACKGROUND: A gene responsible for an inherited predisposition to breast and ovarian cancer has been localized to the long arm of chromosome 17 and termed BRCA1. As well as being closely linked to breast/ovarian cancer cases, this gene may be involved in up to 45% of site-specific breast cancers....
Topics
- Animals
- Breast Neoplasms
- Chromosomes, Human, Pair 17
- ErbB Receptors
- Female
- Genes, Retinoblastoma
- Genes, p53
- Humans
- Mammary Neoplasms, Experimental
- Mice
- Molecular Biology
- Mutation
- Oncogenes
- Proto-Oncogene Proteins
- Receptor, ErbB-2