Article
Hypothalamic dopaminergic neurons in prolactin-deficient Ames dwarf mice: localization and quantification of deficit by tyrosine hydroxylase immunocytochemistry.
Journal of neuroendocrinology - 1 Apr 1994
Phelps C J, Carlson S W, Vaccarella M Y
Abstract excerpt
Hypothalamic tuberoinfundibular prolactin-inhibiting neurons show decreased levels and synthesis of dopamine in two types of genetically prolactin-deficient dwarf mice (Snell, Ames) which arise from separate mutations. A reduction to 2% of normal in this neuronal population has been quantified fo...
Topics
- Aging
- Animals
- Dopamine
- Dwarfism
- Female
- Hypothalamus
- Image Processing, Computer-Assisted
- Immunohistochemistry
- Male
- Mice
- Mice, Inbred Strains
- Neurons
- Phenotype
- Prolactin
- Tyrosine 3-Monooxygenase