Article

Dopaminergic Neuron Lesion at the Area of the Biological Clock Pacemaker, Suprachiasmatic Nuclei (SCN) Induces Metabolic Syndrome in Rats

2020-10-21

Abstract excerpt

<title>Abstract</title> <p><bold>Background:</bold> The daily peak in dopaminergic neuronal activity at the area of the biological clock (hypothalamic suprachiasmatic nuclei [SCN]) is diminished in obese/insulin resistant vs lean/insulin sensitive animals. The impact of targeted lesioning of dopamine (DA) neurons specifically at the area surrounding (and that communicate with) the SCN (but not within the SCN itse...

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Literature Corpus work: 648ceb3b-f483-5ada-89cf-440e12d052b0
DOI: 10.21203/rs.3.rs-95028/v1

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