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Article

Mutational Analysis of a Familial Adenomatous Polyposis Pedigree with Bile Duct Polyp Phenotype.

Canadian journal of gastroenterology & hepatology - 1 Jan 2021

Xie Li-Jun, Ruan Dan-Dan, Zhang Jian-Hui, Li Yi, Chen Li, Yan Mao-Lin, Yu Ming-Dian, Luo Jie-Wei, Zhang Hui-Zhen

Abstract excerpt

A large number of colorectal cancers have a genetic background in China. However, due to insufficient awareness, the diagnostic rate remains low and merely 5-6% of colorectal cancer patients are diagnosed with hereditary colorectal cancer. Familial adenomatous polyposis (FAP) is an autosomal dominant genetic disease caused by mutations in the adenomatous polyposis coli (APC) gene. Different mutation sites in APC...

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Identifiers

PMID: 33954154
DOI: 10.1155/2021/6610434
PMCID: PMC8057911

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 6 Sept 2026. Manifest publication-graph-cohort-2026-09-06.1.

Source receipt: pubmed, retrieved 6 Sept 2026.

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