Article
Dengue virus-specific memory T cell responses in human volunteers receiving a live attenuated dengue virus type 2 candidate vaccine.
The Journal of infectious diseases - 1 Jul 1994
Dharakul T, Kurane I, Bhamarapravati N, Yoksan S, Vaughn D W, Hoke C H, Ennis F A
Abstract excerpt
A live attenuated dengue virus type 2 candidate vaccine (16681-PDK53) was evaluated in a phase I trial in 10 nonimmune adult volunteers. The dengue virus-specific memory T cell responses were analyzed as part of this study. Dengue virus-specific T cell proliferative responses were observed in all subjects after stimulating their peripheral blood mononuclear cells with live viruses or noninfectious viral antigens....
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