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Article

Intratumoral heterogeneity for amplified genes in human breast carcinoma.

International journal of cancer - 1 Jul 1994

Lönn U, Lönn S, Nilsson B, Stenkvist B

Abstract excerpt

Intratumoral heterogeneity was studied in human breast cancer by examining separate tumor lesions of individual patients. Tumor samples were obtained from each patient by fine-needle biopsies from 2 to 4 separate tumor lesions. We used a semi-quantitative PCR to distinguish between samples with gene amplification and single gene copy samples. Five genes were analyzed in each biopsy: MDR-1, dihydrofolate...

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Identifiers

PMID: 7912234
DOI: 10.1002/ijc.2910580108

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

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