Article
Intratumoral heterogeneity for amplified genes in human breast carcinoma.
International journal of cancer - 1 Jul 1994
Lönn U, Lönn S, Nilsson B, Stenkvist B
Abstract excerpt
Intratumoral heterogeneity was studied in human breast cancer by examining separate tumor lesions of individual patients. Tumor samples were obtained from each patient by fine-needle biopsies from 2 to 4 separate tumor lesions. We used a semi-quantitative PCR to distinguish between samples with g...
Topics
- Adult
- Aged
- Aged, 80 and over
- Base Sequence
- Biopsy
- Breast Neoplasms
- DNA, Neoplasm
- Drug Resistance
- Electrophoresis
- ErbB Receptors
- Female
- Fibroblast Growth Factor 3
- Fibroblast Growth Factors
- Gene Amplification
- Genetic Variation
- Humans
- Middle Aged
- Molecular Sequence Data