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Intratumoral Heterogeneity of HER2/neu in Breast Cancer?A Rare Event

20 Feb 2007

Abstract excerpt

HER2/neu is overexpressed in about 20% of invasive breast carcinomas. Numerous studies have shown that there is high level of concordance between the HER2/neu status of the primary breast cancer and the metastases of a given patient. Recently, changes in HER2/neu status with tumor progression have been reported, suggesting the possibility of an emerging different tumor clone. Little is known about intratumoral...

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PMID: 17319852
DOI: 10.1111/j.1524-4741.2007.00396.x

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