Article
Keratinocyte transglutaminase expression varies in squamous cell carcinomas.
The Journal of investigative dermatology - 1 Apr 1994
Duvic M, Nelson D C, Annarella M, Cho M, Esgleyes-Ribot T, Remenyik E, Ulmer R, Rapini R P, Sacks P G, Clayman G L
Abstract excerpt
Type I transglutaminase (TGase I, keratinocyte or particulate transglutaminase) is a 92-kilodalton (kDa) protein expressed in abundance in cultured keratinocytes and in the hyperproliferative skin disorder psoriasis. To determine the expression of TGase I protein and mRNA, we studied tissue and established squamous carcinoma lines derived from different sources. Immunohistochemistry and Western blotting were used...
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