Article
Recombinant interleukin-2 corrects in vitro the immunological defect of endometriosis.
American journal of reproductive immunology (New York, N.Y. : 1989) - 1 Dec 1993
Melioli G, Semino C, Semino A, Venturini P L, Ragni N
Abstract excerpt
PROBLEM: It has been shown recently that women with endometriosis have several immunological defects. In particular, these patients have a defect in peripheral blood natural killer cell activity and have lost their capacity of recognizing and lysing autologous endometrial cells. METHOD: We evalua...
Topics
- Antigens, Differentiation, T-Lymphocyte
- Autoimmunity
- CD4-Positive T-Lymphocytes
- CD8 Antigens
- Cells, Cultured
- Cytotoxicity, Immunologic
- Endometriosis
- Female
- Humans
- In Vitro Techniques
- Interleukin-2
- Isoantigens
- Keratinocytes
- Killer Cells, Natural
- Lymphocyte Activation
- Phenotype
- Recombinant Proteins
- T-Lymphocyte Subsets