Article
No effect of TaqI polymorphism at the human renal kallikrein (KLK1) locus on normal blood pressure level or variability.
Clinical genetics - 1 Oct 1993
Berge K E, Berg K
Abstract excerpt
Renal kallikrein is a component of the kallikrein-kinin-system (KKS). Kallikrein has been shown to cleave the precursor kininogen to release small kinins, which cause vasodilatation, increased diuresis and natriuresis. We have studied a normal restriction fragment length polymorphism (RFLP) at the renal kallikrein locus (KLK1), detectable with the restriction enzyme TaqI. In one series of 167 unrelated...
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