No effect of TaqI polymorphism at the human renal kallikrein (KLK1) locus on normal blood pressure level or variability.

doi:10.1111/j.1399-0004.1993.tb03879.x

Back to search

Article

No effect of TaqI polymorphism at the human renal kallikrein (KLK1) locus on normal blood pressure level or variability.

Clinical genetics - 1 Oct 1993

Berge K E, Berg K

Abstract excerpt

Renal kallikrein is a component of the kallikrein-kinin-system (KKS). Kallikrein has been shown to cleave the precursor kininogen to release small kinins, which cause vasodilatation, increased diuresis and natriuresis. We have studied a normal restriction fragment length polymorphism (RFLP) at th...

Topics

Adult
Aged
Blood Pressure
DNA
Female
Genotype
Humans
Hypertension
Kallikreins
Kidney
Male
Middle Aged
Polymorphism, Genetic
Polymorphism, Restriction Fragment Length
Twins, Monozygotic

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

discussions

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.