Allelic association and linkage studies in Wilson disease.

doi:10.1093/hmg/2.9.1401

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Article

Allelic association and linkage studies in Wilson disease.

Human molecular genetics - 1 Sept 1993

Thomas G R, Roberts E A, Rosales T O, Moroz S P, Lambert M A, Wong L T, Cox D W

Abstract excerpt

We have studied 21 families with Wilson disease (WND), using restriction fragment length polymorphisms (RFLPs) in the 13q14.3 region, to measure linkage of these markers to the disease locus. In addition to previously described markers, we include linkage data for a newly isolated marker (D13S86)...

Topics

Alleles
Base Sequence
Chromosome Mapping
Chromosomes, Human, Pair 13
DNA
Female
Genetic Linkage
Genetic Markers
Genotype
Hepatolenticular Degeneration
Humans
Lod Score
Male
Molecular Sequence Data
Pedigree
Polymorphism, Restriction Fragment Length

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