Article
Neuropeptide-Y Y1 receptor gene polymorphism: cross-sectional analyses in essential hypertension and obesity.
Biochemical and biophysical research communications - 29 Oct 1993
Herzog H, Selbie L A, Zee R Y, Morris B J, Shine J
Abstract excerpt
Neuropeptide Y increases blood pressure and appetite, disorders of which have a genetic component. The present study examined the neuropeptide-Y Y1 receptor gene (NPYY1R) for involvement in essential hypertension (HT) and obesity. Frequency of alleles of the only known variant, involving a point...
Topics
- Alleles
- Body Mass Index
- Cross-Sectional Studies
- DNA
- Genetic Carrier Screening
- Genotype
- Humans
- Hypertension
- Leukocytes
- Linkage Disequilibrium
- Middle Aged
- Obesity
- Point Mutation
- Polymorphism, Restriction Fragment Length
- Receptors, Neuropeptide Y
- Reference Values
- Restriction Mapping