Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

Isolation, characterization and evolution of ovine major histocompatibility complex class II DRA and DQA genes.

Animal genetics - 1 Aug 1993

Fabb S A, Maddox J F, Gogolin-Ewens K J, Baker L, Wu M J, Brandon M R

Abstract excerpt

Four full-length ovine major histocompatibility complex (MHC) class II A cDNA clones coding for new alleles of DRA, DQA1 and DQA2 genes were isolated from two ovine lambda gt10 cDNA libraries. The derived amino acid sequences of these clones resemble class II A molecules from other species in both size and structure. Restriction fragment length polymorphism analysis, using an Ovar-DRA probe on DNA from Merino and...

Topics

Alleles
Amino Acid Sequence
Animals
Base Sequence
Biological Evolution
Blotting, Southern
DNA
Genes, MHC Class II
HLA-DQ Antigens
Histocompatibility Antigens Class II
Humans

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Molecular Sequence Data

Polymorphism, Restriction Fragment Length

Sequence Homology, Amino Acid

Sheep

Source

Identifiers

PMID: 7902039
DOI: 10.1111/j.1365-2052.1993.tb00307.x

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7902039-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

Community interpretation

Discuss the evidence

Ask a question, add context or challenge an interpretation. Community activity is separate from scientific evidence strength.

0

discussions

0

replies

Citations encouraged

Claims remain attributable.

No discussion yet

Be the first to add a careful, cited interpretation.

Related research

Semantic proximity does not establish scientific evidence.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

Isolation, characterization and evolution of ovine major histocompatibility complex class II DRA and DQA genes.PMID 7902039Read ↗

Characterization and evolution of ovine MHC class II DQB sequence polymorphism.Semantic proximity Read ↗

Allelic polymorphism in the ovine DQA1 gene.Semantic proximity Read ↗

Polymorphism at the ovine major histocompatibility complex class II loci.Semantic proximity Read ↗

Identification and phylogenetic analysis of 15 MHC class II DRB1 beta1 expressed alleles in a ewe-lamb flock.Semantic proximity Read ↗

Genomic organisation and allelic diversity within coding and non-coding regions of the Ovar-DRB1 locus.Semantic proximity Read ↗

Documentation of extensive genetic diversity in the Ovar-DRB1 gene in native Turkish sheep.Semantic proximity Read ↗

Evolution of the ovine MHC DQA region.Semantic proximity Read ↗

Sequences and diversity of 17 new Ovar-DRB1 alleles from three breeds of sheep.Semantic proximity Read ↗

An ancient interlocus recombination increases class II MHC DQA diversity in sheep and other Bovidae.Semantic proximity Read ↗

Identification of a new bovine MHC class II DRB allele by nucleotide sequencing and an analysis of phylogenetic relationships.Semantic proximity Read ↗

Rapid communication: three new allelic sequences at the ovine MHC class II DQA1 locus.Semantic proximity Read ↗

Restriction fragment length polymorphism of DQB and DRB class II genes of the ovine major histocompatibility complex.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.