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Article

Sequences and diversity of 17 new Ovar-DRB1 alleles from three breeds of sheep.

European journal of immunogenetics : official journal of the British Society for Histocompatibility and Immunogenetics - 1 Aug 2003

Konnai S, Nagaoka Y, Takeshima S, Onuma M, Aida Y

Abstract excerpt

To investigate the genetic diversity of the sheep MHC (Ovar) class II DRB1 locus, we amplified exon 2 of Ovar-DRB1 alleles by polymerase chain reaction (PCR) and determined the nucleotide sequences of both resultant strands after cloning. In our study of a total of 97 sheep of three breeds, namely, Suffolk, Cheviot and Corriedale, we identified 18 previously published alleles and 17 new alleles. These alleles...

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PMID: 12919289
DOI: 10.1046/j.1365-2370.2003.00399.x

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