Article
Durable remission in a patient of mixed phenotype acute leukemia with Philadelphia chromosome-positive treated with nilotinib and lenalidomide: A case report.
Medicine - 1 Apr 2018
Lai Binbin, Mu Qitian, Zhu Huiling, Wang Yi, Zhang Yi, Xu Kaihong, Sheng Lixia, Ouyang Guifang
Abstract excerpt
RATIONALE: Philadelphia chromosome-positive mixed phenotype acute leukemia (Ph+ MPAL) is a rare type of leukemia with poor prognosis. Tyrosine kinase inhibitors (TKIs) in combination with chemotherapy have significantly improved its remission rate. However, relapse remains the major obstacle to achieve long survival. Lenalidomide is a second-generation oral immunomodulatory drug that has been broadly applied in...
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