Discover Community Create You

Loading publication...

Noodle always counts identifier-free feature events for service operation. With your permission, Google Analytics can also estimate audience and engagement. Search text, publication identifiers, cookies, IP addresses and browser fingerprints are never included in Noodle's first-party event counters.

Privacy details

Article

The distribution of mutation effects on viability in Drosophila melanogaster.

Genetics - 1 Dec 1994

Keightley P D

Abstract excerpt

Parameters of continuous distributions of effects and rates of spontaneous mutation for relative viability in Drosophila are estimated by maximum likelihood from data of two published experiments on accumulation of mutations on protected second chromosomes. A model of equal mutant effects gives a poor fit to the data of the two experiments; higher likelihoods are obtained with leptokurtic distributions or for...

Read the complete abstract on PubMed

Topics

Share this publication in a Topic to start or enrich a Post.

Share to Computer Simulation
Share to Drosophila melanogaster
Share to Genes, Lethal

Methodology Data sources Editorial policy Privacy Delete account & data About Contact Helena Bioinformatics

Share to Genotype

Share to Likelihood Functions

Share to Longevity

Share to Models, Genetic

Share to Mutation

Source

Open in PubMed Open full text

Identifiers

PMID: 7896110
DOI: 10.1093/genetics/138.4.1315
PMCID: PMC1206267

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 7 Sept 2026. Manifest publication-graph-cohort-2026-09-08.1.

Source receipt: pubmed, retrieved 7 Sept 2026.

Related research

Semantic proximity does not establish scientific evidence. Graph snapshot: 2026-09-29.

Research trail→

Click a neighbor to travelStep 1 · 12 closest

The distribution of mutation effects on viability in Drosophila melanogaster.PMID 7896110Read ↗

The mutation rate and the distribution of mutational effects of viability and fitness in Drosophila melanogaster.Semantic proximity Read ↗

Sex-specific viability effects of mutations in Drosophila melanogaster.Semantic proximity Read ↗

New estimates of the rates and effects of mildly deleterious mutation in Drosophila melanogaster.Semantic proximity Read ↗

Environment dependence of mutational parameters for viability in Drosophila melanogaster.Semantic proximity Read ↗

On the rate and linearity of viability declines in Drosophila mutation-accumulation experiments: genomic mutation rates and synergistic epistasis revisited.Semantic proximity Read ↗

Nature of deleterious mutation load in Drosophila.Semantic proximity Read ↗

Genetic variation for preadult viability in Drosophila melanogaster.Semantic proximity Read ↗

Accumulation of deleterious mutations: additional Drosophila melanogaster estimates and a simulation of the effects of selection.Semantic proximity Read ↗

Mutation-selection balance accounting for genetic variation for viability in Drosophila melanogaster as deduced from an inbreeding and artificial selection experiment.Semantic proximity Read ↗

The genomic mutation rate for fitness in Drosophila.Semantic proximity Read ↗

The rate of mutation and the homozygous and heterozygous mutational effects for competitive viability: a long-term experiment with Drosophila melanogaster.Semantic proximity Read ↗

Dominance of mutations affecting viability in Drosophila melanogaster.Semantic proximity Read ↗

⌁Select a neighboring publication to make it the new centre.