The distribution of mutation effects on viability in Drosophila melanogaster.

doi:10.1093/genetics/138.4.1315

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Article

The distribution of mutation effects on viability in Drosophila melanogaster.

Genetics - 1 Dec 1994

Keightley P D

Abstract excerpt

Parameters of continuous distributions of effects and rates of spontaneous mutation for relative viability in Drosophila are estimated by maximum likelihood from data of two published experiments on accumulation of mutations on protected second chromosomes. A model of equal mutant effects gives a...

Topics

Animals
Computer Simulation
Drosophila melanogaster
Genes, Lethal
Genotype
Likelihood Functions
Longevity
Models, Genetic
Monte Carlo Method
Mutation

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