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Article

Dominance of mutations affecting viability in Drosophila melanogaster.

Genetics - 1 Apr 2003

Fry James D, Nuzhdin Sergey V

Abstract excerpt

There have been several attempts to estimate the average dominance (ratio of heterozygous to homozygous effects) of spontaneous deleterious mutations in Drosophila melanogaster, but these have given inconsistent results. We investigated whether transposable element (TE) insertions have higher average dominance for egg-to-adult viability than do point mutations, a possibility suggested by the types of...

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Identifiers

PMID: 12702680
DOI: 10.1093/genetics/163.4.1357
PMCID: PMC1462516

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