Article
The Drosophila giant lens gene plays a dual role in eye and optic lobe development: inhibition of differentiation of ommatidial cells and interference in photoreceptor axon guidance.
Mechanisms of development - 1 Dec 1994
Brunner A, Twardzik T, Schneuwly S
Abstract excerpt
The Drosophila giant lens (gil) gene encodes a secreted molecule which if absent leads to the recruitment of additional ommatidial cells normally eliminated by apoptosis. Heat induced ectopic gil expression leads to a reduction of ommatidial cells suggesting that gil is secreted by differentiatin...
Topics
- Animals
- Axons
- Cell Differentiation
- Drosophila
- Eye
- Gene Expression Regulation, Developmental
- Genes, Insect
- Hot Temperature
- Mutation
- Optic Lobe, Nonmammalian
- Photoreceptor Cells, Invertebrate