Article
Multiple roles for DNA polymerase I in establishment and replication of the promiscuous plasmid pLS1.
Molecular microbiology - 1 Nov 1994
Díaz A, Lacks S A, López P
Abstract excerpt
The polymerase activity of DNA polymerase I is important for the establishment of the pLS1 replicon by reconstitutive assembly in Streptococcus pneumoniae after uptake of exogenous pLS1 plasmid DNA. In polA mutants lacking the polymerase domain, such establishment was reduced at least 10-fold in...
Topics
- DNA Polymerase I
- DNA Replication
- Gene Transfer Techniques
- Genes, Bacterial
- Models, Biological
- Mutation
- Plasmids
- Replicon
- Streptococcus pneumoniae