Testing for linkage: phase known/unknown.

doi:10.1093/oxfordjournals.jhered.a111528

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Article

Testing for linkage: phase known/unknown.

The Journal of heredity - 1 Jan 2000

Doerge R W

Abstract excerpt

It has been well established in human genetics that when one is testing for linkage between two loci, the significance test must be one-sided for the purpose of reflecting the theoretical limits placed on the estimated recombination fraction. However, the issue becomes obscure when phase-known/-u...

Topics

Alleles
Crosses, Genetic
Genetic Linkage
Genotype
Humans
Models, Genetic
Recombination, Genetic

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