Prediction of linkage phase by parental phenotypes.

Abstract excerpt

This paper answers the question as to which parental phenotypes are useful in prediction of the linkage phase of the progeny under conditions of linkage equilibrium. I demonstrate that 1) the parents with the same disease status or marker genotype carry no information about phase of the diheterozygous offspring; 2) the linkage phase can be inferred unambiguously only under recessive or dominant control of...

Topics

Share this publication in a Topic to start or enrich a Post.

• Share to Genetic Markers
• Share to Linkage Disequilibrium
• Share to Models, Genetic