Increased Na+/Mg2+ antiport in erythrocytes of patients with cystic fibrosis.

doi:10.1515/cclm.1994.32.11.833

Article

Increased Na+/Mg2+ antiport in erythrocytes of patients with cystic fibrosis.

European journal of clinical chemistry and clinical biochemistry : journal of the Forum of European Clinical Chemistry Societies - 1 Nov 1994

Vormann J, Magdorf K, Günther T, Wahn U

Abstract excerpt

Na+/Mg2+ antiport and Na(+)-independent Mg2+ efflux were investigated in erythrocytes of 41 patients with cystic fibrosis and 26 controls. Na(+)-independent Mg2+ efflux was unchanged in cystic fibrosis, but a significantly increased activity of Na+/Mg2+ antiport was detected (control: 0.16 +/- 0.02, cystic fibrosis: 0.39 +/- 0.06, Mg2+ efflux, mmol/30 min x 1 cells, mean +/- SEM, p < 0.01). An increased activity...

Topics

Adolescent
Adult
Antiporters
Child
Cystic Fibrosis
Erythrocytes
Female
Genotype
Humans
Magnesium
Male
Mutation

Sodium

Sweat

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