Article
[Familial hemiplegic migraine. Localization of a responsible gene on chromosome 19].
Revue neurologique - 1 Jan 1994
Joutel A, Bousser M G, Biousse V, Labauge P, Chabriat H, Nibbio A, Maciazek J, Meyer B, Bach M A, Weissenbach J
Abstract excerpt
Familial hemiplegic migraine is an autosomal dominant disorder of unknown pathogenesis in which the migrainous attacks are marked by the occurrence of a transient hemiplegia during the aura. The aim of our study was the identification of the affected gene. The first step was the chromosomal mapping of the affected gene, for which we used a "candidate gene" strategy. The first candidate gene was the gene...
Topics
- Chromosomes, Human, Pair 19
- Female
- Genetic Linkage
- Hemiplegia
- Humans
- Male
- Migraine Disorders
- Mutation
- Pedigree