Article
[Molecular genetic findings in migraine].
Ugeskrift for laeger - 5 Nov 2001
Østergaard E, Thomsen L L, Russell M B
Abstract excerpt
This review focuses on the different molecular genetic findings in migraine. Familial hemiplegic migraine (FHM) is a rare subtype of migraine with aura, which is inherited as an autosomal dominant. Half the cases of FHM are caused by point mutations in the CACNA1A gene on the short arm of chromosome 19 (19p). The gene encodes a calcium ion channel. Other mutation types cause episodic ataxia 2 (EA-2). Expansions...
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