Article
Fasciclin III as a synaptic target recognition molecule in Drosophila.
Nature - 9 Mar 1995
Chiba A, Snow P, Keshishian H, Hotta Y
Abstract excerpt
Fasciclin III, a cell adhesion molecule of the immunoglobulin superfamily, is expressed by motor neuron RP3 and its synaptic targets (muscle cells 6 and 7) during embryonic neuromuscular development of Drosophila. We report here that RP3 often incorrectly innervates neighbouring non-target muscle cells when these cells misexpress fasciclin III, but still innervates normal targets in the fasciclin III null mutant....
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