Article
HLA class II alleles confer susceptibility to recurrent fetal losses in Danish women.
Tissue antigens - 1 Oct 1994
Christiansen O B, Rasmussen K L, Jersild C, Grunnet N
Abstract excerpt
HLA-DR and -DQ typings were performed by a combination of RFLP and PCR-SSP techniques in 234 Danish women with at least three consecutive unexplained fetal losses (recurrent fetal losses) and 360 controls and the DRB1, DQA1 and DQB1 alleles were deduced. In the total group of patients, the freque...
Topics
- Abortion, Habitual
- Alleles
- Denmark
- Deoxyribonucleases, Type II Site-Specific
- Female
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-DQ Antigens
- HLA-DQ alpha-Chains
- HLA-DQ beta-Chains
- Haplotypes
- Humans
- Polymerase Chain Reaction
- Polymorphism, Restriction Fragment Length
- Pregnancy