Article
Angiotensin-converting enzyme DD genotype, angiotensin type 1 receptor CC genotype, and hyperhomocysteinemia increase first-trimester fetal-loss susceptibility.
Blood coagulation & fibrinolysis : an international journal in haemostasis and thrombosis - 1 Oct 2000
Fatini C, Gensini F, Battaglini B, Prisco D, Cellai A P, Fedi S, Marcucci R, Brunelli T, Mello G, Parretti E, Pepe G, Abbate R
Abstract excerpt
Complications of pregnancy have been found to be related with thrombophilic polymorphisms that explain about 30% of obstetric complications. We evaluated the angiotensin converting enzyme (ACE) and the angiotensin type 1 receptor (AT1R) gene polymorphisms in the renin-angiotensin system (RAS) as possible risk factors for fetal loss. Fifty-nine women with a history of three or more first-trimester fetal losses and...
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