Article
Studies of RFLP-inferred HLA-DR-DQ haplotypes in Danish women with recurrent fetal losses.
Tissue antigens - 1 Sept 1992
Christiansen O B, Mathiesen O, Husth M, Jersild C, Grunnet N
Abstract excerpt
Results of HLA-DR and -DQ typing by RFLP in 152 unrelated women with at least 3 unexplained fetal losses were compared with those of 210 normal controls. The overall distribution of DR-DQ phenotypes did not differ significantly between patients and controls. In a subgroup of 59 patients having had at least 4 fetal losses, a significantly higher number of patients than controls were DRw17,DQw2-positive (RR = 2.9,...
Topics
- Abortion, Habitual
- Adult
- Denmark
- Disease Susceptibility
- Female
- Gene Frequency
- Genes, MHC Class II
- Genetic Predisposition to Disease
- HLA-D Antigens
- HLA-DQ Antigens
- HLA-DR Antigens
