Article
Adaptation of Xanthobacter autotrophicus GJ10 to bromoacetate due to activation and mobilization of the haloacetate dehalogenase gene by insertion element IS1247.
Journal of bacteriology - 1 Mar 1995
van der Ploeg J, Willemsen M, van Hall G, Janssen D B
Abstract excerpt
Monobromoacetate (MBA) is toxic for the 1,2-dichloroethane-degrading bacterium Xanthobacter autotrophicus GJ10 at concentrations higher than 5 mM. Mutants which are able to grow on higher concentrations of MBA were isolated and found to overexpress haloacid dehalogenase, which is encoded by the d...
Topics
- Acetates
- Adaptation, Physiological
- Amino Acid Sequence
- Base Sequence
- Biodegradation, Environmental
- DNA Transposable Elements
- Drug Resistance, Microbial
- Gene Expression Regulation, Bacterial
- Genes, Bacterial
- Gram-Negative Aerobic Bacteria
- Halogens
- Hydrolases
- Molecular Sequence Data
- Mutation