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Article

Carbon and energetic uncoupling are associated with block of division at different stages of the cell cycle in several cdc mutants of Saccharomyces cerevisiae.

Experimental cell research - 1 Mar 1995

Aon M A, Mónaco M E, Cortassa S

Abstract excerpt

Cell proliferation arrest at 37 degrees C (restrictive temperature) of the cell division cycle (cdc) mutants of Saccharomyces cerevisiae cdc28, cdc35, cdc19, cdc21, and cdc17 was correlated with carbon and energy uncoupling. At 37 degrees C, cdc mutants diverted to biomass synthesis only 3 to 4% and 8 to 24% of the fluxes of carbon consumed and ATP obtained by catabolism, respectively, compared with 48 and 34% in...

Topics

Carbon
Cell Cycle
Cell Cycle Proteins
Cell Division
Energy Metabolism
Ethanol
Fermentation
Macromolecular Substances
Mutation
Oxyquinoline
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

Saccharomyces cerevisiae

Temperature

Source

Identifiers

PMID: 7867719
DOI: 10.1006/excr.1995.1061

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7867719-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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