Article
SDC25, a dispensable Ras guanine nucleotide exchange factor of Saccharomyces cerevisiae differs from CDC25 by its regulation.
Molecular biology of the cell - 1 Apr 1996
Boy-Marcotte E, Ikonomi P, Jacquet M
Abstract excerpt
The SDC25 gene of Saccharomyces cerevisiae is homologous to CDC25. Its 3' domain encodes a guanine nucleotide exchange factor (GEF) for Ras. Nevertheless, the GEF encoded by CDC24 is determinant for the Ras/cAMP pathway activation in growth. We demonstrate that the SDC25 gene product is a functio...
Topics
- Base Sequence
- Blotting, Northern
- Cell Cycle Proteins
- Fungal Proteins
- GTP-Binding Proteins
- Gene Expression Regulation, Fungal
- Molecular Sequence Data
- Open Reading Frames
- Phenotype
- Saccharomyces cerevisiae
- Transcription Factors
- Transcription, Genetic
- rap GTP-Binding Proteins
- ras-GRF1