Article
Genetic predisposition to hypertension (as detected by Na+/Li+ countertransport) and risk of diabetic nephropathy in childhood diabetes.
Journal of paediatrics and child health - 1 Dec 1994
Chiarelli F, Verrotti A, Kalter-Leibovici O, Laron Z, Morgese G
Abstract excerpt
In order to evaluate whether insulin-dependent diabetes mellitus patients with incipient nephropathy have an overactivity of erythrocyte sodium-lithium countertransport (Na+/Li+ CT), 82 diabetic children and 38 healthy age-matched control subjects and their parents and grandparents were studied....
Topics
- Adolescent
- Adult
- Albuminuria
- Antiporters
- Case-Control Studies
- Causality
- Child
- Diabetes Mellitus, Type 1
- Diabetic Nephropathies
- Erythrocytes
- Genetic Predisposition to Disease
- Humans
- Hypertension
- Lithium
- Matched-Pair Analysis
- Sodium