Article
Hepatitis B E antigen detection in formalin-fixed liver biopsy specimens. A tool to investigate wild-type and E-minus variant HBV infection.
American journal of clinical pathology - 1 Feb 1995
Villari D, Pollicino T, Spinella S, Russo F, Campo S, Rodino G, Squadrito G, Longo G, Raimondo G
Abstract excerpt
The aim of this study is to investigate whether hepatitis B e antigen (HBeAg) reactivity can be detected on formalin-fixed, paraffin-embedded liver tissue, and whether immunohistochemical detection of intrahepatic HBeAg may help to distinguish between "wild-type" and "eminus" hepatitis B virus (H...
Topics
- Adolescent
- Adult
- Aged
- Base Sequence
- Biopsy
- Fixatives
- Formaldehyde
- Genetic Variation
- Genome, Viral
- Hepatitis B
- Hepatitis B e Antigens
- Hepatitis B virus
- Humans
- Liver
- Middle Aged
- Molecular Sequence Data
- Oligonucleotide Probes
- Polymerase Chain Reaction
