Article
[Screening of hemoglobinopathies and molecular analysis of beta-thalassemia in Central Tunisia].
Archives de pediatrie : organe officiel de la Societe francaise de pediatrie - 1 Dec 1994
Chebil-Laradi S, Pousse H, Khelif A, Ghanem N, Martin J, Kortas M, Ennabli S, Mehdouani K, B'Chir N, Kharrat H
Abstract excerpt
BACKGROUND: Previous investigations have permitted to locate 16 beta-thalassemic mutations in different samples of the Tunisian population. One of them (IVS I nt 2: T--G) had been found only in the central region of Tunisia. Our research was carried out in this part of the country to estimate the prevalence of this mutation and to establish a prenatal diagnosis using appropriate probes. POPULATION AND METHODS:...
Topics
- Anemia, Sickle Cell
- Hemoglobinopathies
- Humans
- Molecular Biology
- Mutation
- Polymerase Chain Reaction
- Tunisia
- beta-Thalassemia