Article
Gene targeting and synaptic plasticity.
Current opinion in neurobiology - 1 Oct 1994
Grant S G
Abstract excerpt
Gene targeting is revealing new molecular functions by creating very specific developmental, physiological and behavioral perturbations, and providing new insights into biochemical pathways underlying synaptic plasticity. Recent studies of mice carrying mutations in genes thought to be involved in modulating synaptic transmission have been subject to integrated biochemical, physiological and behavioral analyses.
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