Inhibition of early 3-methyl-4-dimethylaminoazobenzene-induced hepatocarcinogenesis by gomisin A in rats.

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Article

Inhibition of early 3-methyl-4-dimethylaminoazobenzene-induced hepatocarcinogenesis by gomisin A in rats.

Anticancer research - 1 Jan 2000

Nomura M, Ohtaki Y, Hida T, Aizawa T, Wakita H, Miyamoto K

Abstract excerpt

The effects of gomisin A, a lignan component of Schizandra fruits, on hepatocarcinogenesis caused by 3'-methyl-4- dimethylaminoazobenzene (3'-MeDAB) in male Donryu rats were investigated. Gomisin A significantly inhibited the appearance of foci stained for glutathione S-transferase placental form...

Topics

Animals
Anticarcinogenic Agents
Biomarkers, Tumor
Cell Nucleus
Cyclooctanes
Dioxoles
Drugs, Chinese Herbal
Glutathione Transferase
Lignans
Liver
Liver Neoplasms, Experimental
Male
Methyldimethylaminoazobenzene
Phenotype
Ploidies
Rats

Source

Open in PubMed

Identifiers

PMID: 7847835

Provenance

PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 30 Aug 2026. Prepared record publication-7847835-2026-08-30.1. Manifest publication-graph-cohort-2026-08-30.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 30 Aug 2026.

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