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Article

Molecular heterogeneity of hereditary elliptocytosis in Italy.

Haematologica - 1 Jan 2000

Miraglia del Giudice E, Perrotta S, Sannino E, De Angelis F, Nobili B, Iolascon A

Abstract excerpt

BACKGROUND: Common HE is the most prevalent clinical form of hereditary elliptocytosis; its clinical findings vary considerably, ranging from an asymptomatic carrier state to a severe, even life-threatening hemolytic disorder. Structural modification and reduction of 4.1 protein, or abnormalities at the spectrin self-association site could lead to elliptocytes. METHODS: Sixty-one Italian HE patients belonging to...

Topics

Adolescent
Adult
Child
Child, Preschool
Elliptocytosis, Hereditary
Erythrocyte Membrane
Humans
Infant
Italy
Membrane Proteins
Middle Aged
Phenotype

Methodology Data sources Editorial policy Privacy About Contact Helena Bioinformatics

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PMID: 7843625

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PubMed metadata and Literature Corpus relationships. Corpus snapshot updated 29 Aug 2026. Prepared record publication-7843625-2026-08-29.1. Manifest publication-graph-cohort-2026-08-29.1.

Source receipt: PubMed via Helena Literature Corpus, retrieved 29 Aug 2026.

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